https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25787 Wed 11 Apr 2018 16:15:49 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24497 Ex vivo knockdown of these microRNAs restored TLR7 expression with concomitant augmentation of virus-induced IFN production. Conclusions: In severe asthma, TLR7 deficiency drives impaired innate immune responses to virus by AMs. Blocking a group of microRNAs that are up-regulated in these cells can restore antiviral innate responses, providing a novel approach for therapy in asthma.]]> Fri 01 Apr 2022 09:26:07 AEDT ]]>